Publications

2024

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Fichman, Y., Peláez-Vico, M.Á., Mudalige, A.K., Lee, H.-O., Mittler, R., Park, S.-Y., 2024. Rapid plant-to-plant systemic signaling via a Cuscuta bridge. Plant Physiology. kiae339

https://doi.org/10.1093/plphys/kiae339

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Fichman, Y., Rowland, L., Thao, T., Chen, S-J., Mittler, R., 2024. Propagation of a rapid cell-to-cell H2O2 signal over long distances in a monolayer of cardiomyocyte cells. Redox Biology, 103069.

https://doi.org/10.1016/j.redox.2024.103069

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Myers, R.J., Peláez-Vico, M.Á., Fichman, Y., 2024. Functional analysis of reactive oxygen species-driven stress systemic signalling, interplay and acclimation.  Plant Cell & Environment

https://doi.org/10.1111/pce.14894

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Peláez-Vico, M.Á., Fichman, Y., Zandalinas, S.I., Foyer, C.H., Mittler R., 2024. ROS are universal cell-to-cell stress signals.  Current Opinion in Plant Biology, 79, 102540

https://doi.org/10.1016/j.pbi.2024.102540

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Zhou, Y., Fichman, Y., Zhang, S., Mittler R., Chen, S-J., 2024. Modeling the Reactive Oxygen Species (ROS) wave in Chlamydomonas reinhardtii colonies.  Free Radical Biology and Medicine, 222, 165-172

https://doi.org/10.1016/j.freeradbiomed.2024.06.003

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2023

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Fichman, Y., Rowland, L., Oliver, M.J., Mittler, R., 2023. ROS are evolutionary conserved cell-to-cell stress signals. Proceedings of the National Academy of Sciences 120, e2305496120.
https://doi.org/10.1073/pnas.2305496120
 

Fichman, Y., Xiong, H., Sengupta, S., Morrow, J., Loog, H., Azad, R.K., Hibberd, J.M., Liscum, E., Mittler, R., 2023. Phytochrome B regulates reactive oxygen signaling during abiotic and biotic stress in plants. New Phytologist 237, 1711–1727. https://doi.org/10.1111/nph.18626
 

Myers, R.J., Jr, Fichman, Y., Zandalinas, S.I., Mittler, R., 2023. Jasmonic acid and salicylic acid modulate systemic reactive oxygen species signaling during stress responses. Plant Physiology 191, 862–873.
https://doi.org/10.1093/plphys/kiac449
 

2022

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Fichman, Y., Zandalinas, S.I., Peck, S., Luan, S., Mittler, R., 2022. HPCA1 is required for systemic reactive oxygen species and calcium cell-to-cell signaling and plant acclimation to stress. The Plant Cell 34, 4453–4471.
https://doi.org/10.1093/plcell/koac241
 

Honig, A., Eilenberg, H., Zuther, E., Avisar, D., Erster, O., Eshkol, G., Stein, H., Reznik, N., Schuster, S., Belausov, E., 2022. CWLP and PRP940 form plasma-membrane nanodomain complexes with aquaporins, interact with PP2A and contribute to dehydration tolerance. BioRxiv 512913.
https://doi.org/10.1101/2022.10.20.512913
 

McInturf, S.A., Khan, M.A., Gokul, A., Castro-Guerrero, N.A., Höhner, R., Li, J., Marjault, H.-B., Fichman, Y., Kunz, H.-H., Goggin, F.L., Keyster, M., Nechushtai, R., Mittler, R., Mendoza-Cózatl, D.G., 2022. Cadmium interference with iron sensing reveals transcriptional programs sensitive and insensitive to reactive oxygen species. Journal of Experimental Botany 73, 324–338. https://doi.org/10.1093/jxb/erab393
 

Mittler, R., Zandalinas, S.I., Fichman, Y., Van Breusegem, F., 2022. Reactive oxygen species signalling in plant stress responses. Nature Reviews Molecular Cell Biology 23, 663–679.
https://doi.org/10.1038/s41580-022-00499-2
 

Myers Jr, R.J., Fichman, Y., Stacey, G., Mittler, R., 2022. Extracellular ATP plays an important role in systemic wound response activation. Plant Physiology 189, 1314–1325.
https://doi.org/10.1093/plphys/kiac148
 

Peláez-Vico, M.Á., Fichman, Y., Zandalinas, S.I., Van Breusegem, F., Karpiński, S.M., Mittler, R., 2022. ROS and redox regulation of cell-to-cell and systemic signaling in plants during stress. Free Radical Biology and Medicine 193, 354–362. https://doi.org/10.1016/j.freeradbiomed.2022.10.305
 

Shrestha, H.K., Fichman, Y., Engle, N.L., Tschaplinski, T.J., Mittler, R., Dixon, R.A., Hettich, R.L., Barros, J., Abraham, P.E., 2022. Multi-omic characterization of bifunctional peroxidase 4-coumarate 3-hydroxylase knockdown in Brachypodium distachyon provides insights into lignin modification-associated pleiotropic effects. Frontiers in Plant Science 13, 908649. https://doi.org/10.3389/fpls.2022.908649
 

Sinha, R., Zandalinas, S.I., Fichman, Y., Sen, S., Zeng, S., Gómez‐Cadenas, A., Joshi, T., Fritschi, F.B., Mittler, R., 2022. Differential regulation of flower transpiration during abiotic stress in annual plants. New Phytologist 235, 611–629. https://doi.org/10.1111/nph.18162
 

Szechyńska-Hebda, M., Lewandowska, M., Witoń, D., Fichman, Y., Mittler, R., Karpiński, S.M., 2022. Aboveground plant-to-plant electrical signaling mediates network acquired acclimation. The Plant Cell 34, 3047–3065.
https://doi.org/10.1093/plcell/koac150
 

2021

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Cohen, I., Zandalinas, S.I., Fritschi, F.B., Sengupta, S., Fichman, Y., Azad, R.K., Mittler, R., 2021. The impact of water deficit and heat stress combination on the molecular response, physiology, and seed production of soybean. Physiologia Plantarum 172, 41–52. https://doi.org/10.1111/ppl.13269
 

Devireddy, A.R., Zandalinas, S.I., Fichman, Y., Mittler, R., 2021. Integration of reactive oxygen species and hormone signaling during abiotic stress. The Plant Journal 105, 459–476.
https://doi.org/10.1111/tpj.15010
 

Fichman, Y., Mittler, R., 2021. A systemic whole-plant change in redox levels accompanies the rapid systemic response to wounding. Plant Physiology 186, 4–8.
https://doi.org/10.1093/plphys/kiab022
 

Fichman, Y., Mittler, R., 2021. Integration of electric, calcium, reactive oxygen species and hydraulic signals during rapid systemic signaling in plants. The Plant Journal 107, 7–20.
https://doi.org/10.1111/tpj.15360
 

Fichman, Y., Myers, R.J., Grant, D.G., Mittler, R., 2021. Plasmodesmata-localized proteins and ROS orchestrate light-induced rapid systemic signaling in Arabidopsis. Science Signaling 14, eabf0322.
https://doi.org/10.1126/scisignal.abf0322
 

Zhu, Q., Hao, H., Xu, H., Fichman, Y., Cui, Y., Yang, C., Wang, M., Mittler, R., Hill, M.A., Cowan, P.J., Zhang, G., He, X., Zhou, S., Liu, Z., 2021. Combination of Antioxidant Enzyme Overexpression and N‐Acetylcysteine Treatment Enhances the Survival of Bone Marrow Mesenchymal Stromal Cells in Ischemic Limb in Mice With Type 2 Diabetes. Journal of the American Heart Association 10, e023491. https://doi.org/10.1161/JAHA.121.023491
 

2020

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Czarnocka, W., Fichman, Y., Bernacki, M., Różańska, E., Sańko-Sawczenko, I., Mittler, R., Karpiński, S., 2020. FMO1 Is Involved in Excess Light Stress-Induced Signal Transduction and Cell Death Signaling. Cells 9, 2163.
https://doi.org/10.3390/cells9102163
 

Fichman, Y., Mittler, R., 2020. Noninvasive Live ROS Imaging of Whole Plants Grown in Soil. Trends in Plant Science 25, 1052–1053. https://doi.org/10.1016/j.tplants.2020.05.003
 

Fichman, Y., Mittler, R., 2020. Rapid systemic signaling during abiotic and biotic stresses: is the ROS wave master of all trades? The Plant Journal 102, 887–896.
https://doi.org/10.1111/tpj.14685
 

Fichman, Y., Zandalinas, S.I., Mittler, R., 2020. Untangling the ties that bind different systemic signals in plants. Science Signaling 13, eabb9505.
https://doi.org/10.1126/scisignal.abb9505
 

Fichman, Y., Zandalinas, S.I., Sengupta, S., Burks, D., Myers, R.J., Jr., Azad, R.K., Mittler, R., 2020. MYB30 Orchestrates Systemic Reactive Oxygen Signaling and Plant Acclimation. Plant Physiology 184, 666–675.
https://doi.org/10.1104/pp.20.00859
 

Zandalinas, S.I., Fichman, Y., Devireddy, A.R., Sengupta, S., Azad, R.K., Mittler, R., 2020. Systemic signaling during abiotic stress combination in plants. Proceedings of the National Academy of Sciences 117, 13810–13820. https://doi.org/10.1073/pnas.2005077117
 

Zandalinas, S.I., Fichman, Y., Mittler, R., 2020. Vascular Bundles Mediate Systemic Reactive Oxygen Signaling during Light Stress. The Plant Cell 32, 3425–3435.
https://doi.org/10.1105/tpc.20.00453

 

2019
 

Fichman, Y., Miller, G., Mittler, R., 2019. Whole-plant live imaging of reactive oxygen species. Molecular Plant 12, 1203–1210.
https://doi.org/10.1016/j.molp.2019.06.003
 

Fromm, H., Fichman, Y., 2019. Water Sensing in Plants, in: Sopory, S. (Ed.), Sensory Biology of Plants. Springer, Singapore, pp. 79–94.
​https://doi.org/10.1007/978-981-13-8922-1_4

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2018
 

Fichman, Y., Koncz, Z., Reznik, N., Miller, G., Szabados, L., Kramer, K., Nakagami, H., Fromm, H., Koncz, C., Zilberstein, A., 2018. SELENOPROTEIN O is a chloroplast protein involved in ROS scavenging and its absence increases dehydration tolerance in Arabidopsis thaliana. Plant Science 270, 278–291.
https://doi.org/10.1016/j.plantsci.2018.02.023
 

2015

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Fichman, Y., Gerdes, S.Y., Kovács, H., Szabados, L., Zilberstein, A., Csonka, L.N., 2015. Evolution of proline biosynthesis: enzymology, bioinformatics, genetics, and transcriptional regulation. Biological Reviews 90, 1065–1099.
https://doi.org/10.1111/brv.12146